Mounjaro

• Do not use if you:

  • Are allergic to tirzepatide or any of the ingredients in Mounjaro.
  • Have a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN 2).
  • Are pregnant, planning to become pregnant, or breastfeeding.

• Consult a doctor before use if you:

  • Have a history of pancreatitis, gallbladder issues, or kidney disease.
  • Are taking other medications to manage blood sugar, such as insulin or sulfonylureas, as combining these with Mounjaro can increase the risk of hypoglycemia (low blood sugar).
  • Have gastrointestinal issues, as Mounjaro may cause digestive side effects.

• Discontinue use and seek medical attention if:

  • You experience severe stomach pain, nausea, or vomiting (possible signs of pancreatitis).
  • You notice swelling in your neck or throat or experience difficulty swallowing (potential signs of thyroid issues).
  • You develop gallbladder symptoms like pain in the upper right abdomen, fever, or jaundice.

• Not suitable for use in children: Mounjaro has not been studied in people under 18 years of age and is not approved for pediatric use.

• Keep out of reach of children: This is a prescription medication and should only be used by individuals for whom it is prescribed.

• Dosage:
  Mounjaro is administered as a once-weekly injection, with the starting dose typically at 2.5 mg. Your healthcare provider may gradually increase the dosage depending on your response to the medication and your treatment plan.

• Administration:
  Inject Mounjaro under the skin (subcutaneous injection) in the abdomen, thigh, or upper arm. Rotate injection sites to prevent irritation. Follow the instructions provided by your healthcare provider for proper injection technique.

• Take with or without food:
  Mounjaro can be injected at any time of day, with or without meals. Ensure that you maintain a healthy diet and exercise routine for the best results.

• Do not exceed the prescribed dose:
  If you miss a dose, take it as soon as possible unless your next dose is due in less than 48 hours. Never double up on doses.

• Store properly:
  Store Mounjaro in the refrigerator until use. Once taken out of the fridge, it can be kept at room temperature for a short time, as advised by your healthcare provider.

Active Ingredient:

• Tirzepatide (varied dosages starting at 2.5 mg): A dual GIP and GLP-1 receptor agonist that helps manage blood sugar and supports weight loss.

Inactive Ingredients:

• Disodium phosphate dihydrate
• Sodium chloride
• Water for injections
• Hydrochloric acid and/or sodium hydroxide (for pH adjustment)

These ingredients ensure the stability and proper delivery of the active compound.

Common Side Effects:

1. Nausea: A common reaction, especially in the early stages of treatment.
2. Diarrhea or constipation: Digestive upset is frequently reported but may improve over time.
3. Vomiting: Can occur, particularly as the body adjusts to the medication.

Less Common but Serious Side Effects:

1. Pancreatitis: Symptoms include severe abdominal pain, nausea, and vomiting. Seek immediate medical attention if these occur.
2. Gallbladder problems: Pain in the upper right abdomen or jaundice could indicate gallstones or other gallbladder issues.
3. Low blood sugar (hypoglycemia): Particularly if Mounjaro is used with other diabetes medications like insulin.

Rare Side Effects:

1. Thyroid tumors: Report any neck swelling, difficulty swallowing, or hoarseness to your doctor.
2. Kidney problems: Signs include reduced urine output and swelling in the hands and feet.
3. Allergic reactions: Rash, itching, or swelling of the face or throat may indicate an allergic response.

• How does Mounjaro work for type 2 diabetes?
  Mounjaro combines GIP and GLP-1 receptor agonists to stimulate insulin production, reduce the liver's glucagon output, and slow digestion. This dual-action mechanism helps lower blood sugar levels and control appetite.

• How does Mounjaro aid in weight loss?
  Mounjaro reduces appetite and increases the feeling of fullness, leading to a lower calorie intake. When used alongside a healthy diet and exercise, it supports significant weight loss.

• How is Mounjaro administered?
  Mounjaro is given as a once-weekly subcutaneous injection (under the skin). You can inject it in the abdomen, thigh, or upper arm. A healthcare provider will show you how to properly administer the injection.

• Are there any side effects?
  Common side effects include nausea, vomiting, diarrhea, and stomach pain. Serious side effects, such as pancreatitis or gallbladder problems, are rare but possible.

• Can Mounjaro be used by individuals without diabetes?
  Mounjaro is primarily approved for type 2 diabetes management, but it may be prescribed off-label for weight loss in individuals with obesity or those who are overweight with weight-related health conditions. Always consult a healthcare provider for personalized advice.